ABCB8 (NM_007188) Human Tagged ORF Clone Lentiviral Particle

SKU RC224948L3V

Lenti ORF particles, ABCB8 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family B (MDR/TAP), member 8 (ABCB8), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: ABCB8
• Synonyms: EST328128; M-ABC1; MABC1; MITOSUR
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224948).
• ACCN: NM_007188
• ORF Size: 2154 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_007188.2, NP_009119.1
• RefSeq Size: 2439 bp
• RefSeq ORF: 2157 bp
• Locus ID: 11194
• UniProt ID: Q9NUT2
• Cytogenetics: 7q36.1
• Domains: AAA, ABC_membrane, ABC_tran
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ABC transporters
• MW: 77.9 kDa
• Summary: This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]