ATP7A (NM_000052) Human Tagged ORF Clone Lentiviral Particle

SKU RC224789L3V

Lenti ORF particles, ATP7A (Myc-DDK tagged) - Human ATPase, Cu++ transporting, alpha polypeptide (ATP7A), 200ul, >10^7 TU/mL. Note: ORF is codon optimized

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: ATP7A
• Synonyms: DSMAX; MK; MNK; SMAX3
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224789).
• ACCN: NM_000052
• ORF Size: 4500 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000052.2
• RefSeq Size: 8492 bp
• RefSeq ORF: 4503 bp
• Locus ID: 538
• UniProt ID: Q04656
• Cytogenetics: Xq21.1
• Domains: E1-E2_ATPase, HMA, Hydrolase
• Protein Families: Druggable Genome, Transmembrane
• MW: 163.4 kDa
• Summary: This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed. [provided by RefSeq, Aug 2013]