ROR1 (NM_001083592) Human Tagged ORF Clone Lentiviral Particle

SKU RC224765L2V

Lenti ORF particles, ROR1 (mGFP-tagged) - Human receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: ROR1
• Synonyms: dJ537F10.1; NTRKR1
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224765).
• ACCN: NM_001083592
• ORF Size: 1179 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001083592.1, NP_001077061.1
• RefSeq Size: 2303 bp
• RefSeq ORF: 1182 bp
• Locus ID: 4919
• UniProt ID: Q01973
• Cytogenetics: 1p31.3
• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• MW: 43.6 kDa
• Summary: This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]