Lamin B Receptor (LBR) (NM_194442) Human Tagged ORF Clone Lentiviral Particle

SKU RC224569L4V

Lenti ORF particles, LBR (mGFP-tagged) - Human lamin B receptor (LBR), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Lamin B Receptor
• Synonyms: C14SR; DHCR14B; LMN2R; PHA; PHASK; TDRD18
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224569).
• ACCN: NM_194442
• ORF Size: 1845 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_194442.1
• RefSeq Size: 3827 bp
• RefSeq ORF: 1848 bp
• Locus ID: 3930
• UniProt ID: Q14739
• Cytogenetics: 1q42.12
• Protein Families: Druggable Genome, Transmembrane
• MW: 70.7 kDa
• Summary: The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]