Lamin B Receptor (LBR) Rabbit Polyclonal Antibody

SKU TA350128

Rabbit Polyclonal Anti-LBR Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 500-2000; WB positive control: Human fetal brain tissue; IHC: 50-200; Positive control: Human ovarian cancer; Predicted cell location: Nucleus
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human LBR
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 71 kDa
• Gene Name: lamin B receptor
• Database Link:
  NP_919424
  Q14739
• Background: The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
• Synonyms: DHCR14B; LMN2R; PHA; TDRD18

Reference Data

• Protein Families: Druggable Genome, Transmembrane