VRK3 (NM_016440) Human Tagged ORF Clone Lentiviral Particle

SKU RC224292L2V

Lenti ORF particles, VRK3 (mGFP-tagged) - Human vaccinia related kinase 3 (VRK3), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: VRK3
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224292).
• ACCN: NM_016440
• ORF Size: 1422 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_016440.3
• RefSeq Size: 2129 bp
• RefSeq ORF: 1425 bp
• Locus ID: 51231
• UniProt ID: Q8IV63
• Cytogenetics: 19q13.33
• Domains: S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• MW: 52.9 kDa
• Summary: This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]