LYPD8 (NM_001085474) Human Tagged ORF Clone Lentiviral Particle
SKU
RC224218L3V
Lenti ORF particles, LYPD8 (Myc-DDK-tagged)-Human phospholipase inhibitor (LOC646627), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | LYPD8 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC224218).
|
ACCN | NM_001085474 |
ORF Size | 711 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_001085474.1, NP_001078943.1 |
RefSeq Size | 1205 bp |
RefSeq ORF | 714 bp |
Locus ID | 646627 |
UniProt ID | Q6UX82 |
Cytogenetics | 1q44 |
MW | 25.1 kDa |
Summary | Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis.[UniProtKB/Swiss-Prot Function] |
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