TRIOBP (NM_138632) Human Tagged ORF Clone Lentiviral Particle

SKU RC224094L4V

Lenti ORF particles, TRIOBP (mGFP-tagged) - Human TRIO and F-actin binding protein (TRIOBP), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: TRIOBP
• Synonyms: DFNB28; dJ37E16.4; HRIHFB2122; TAP68; TARA
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224094).
• ACCN: NM_138632
• ORF Size: 1293 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_138632.2, NP_619538.2
• RefSeq Size: 1743 bp
• RefSeq ORF: 1296 bp
• Locus ID: 11078
• UniProt ID: Q9H2D6
• Cytogenetics: 22q13.1
• Domains: PH
• MW: 47.4 kDa
• Summary: This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Nov 2008]