NRIP (DCAF6) (NM_018442) Human Tagged ORF Clone Lentiviral Particle

SKU RC222570L3V

Lenti ORF particles, DCAF6 (Myc-DDK tagged) - Human DDB1 and CUL4 associated factor 6 (DCAF6), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: NRIP
• Synonyms: 1200006M05Rik; ARCAP; IQWD1; MSTP055; NRIP; PC326
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC222570).
• ACCN: NM_018442
• ORF Size: 2640 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_018442.2, NP_060912.2
• RefSeq Size: 3303 bp
• RefSeq ORF: 2643 bp
• Locus ID: 55827
• UniProt ID: Q58WW2
• Cytogenetics: 1q24.2
• Domains: IQ, WD40
• MW: 98.2 kDa
• Summary: The protein encoded by this gene is a ligand-dependent coactivator of nuclear receptors, including nuclear receptor subfamily 3 group C member 1 (NR3C1), glucocorticoid receptor (GR), and androgen receptor (AR). The encoded protein and DNA damage binding protein 2 (DDB2) may act as tumor promoters and tumor suppressors, respectively, by regulating the level of androgen receptor in prostate tissues. In addition, this protein can act with glucocorticoid receptor to promote human papillomavirus gene expression. [provided by RefSeq, Mar 2017]