Intersectin 1 (ITSN1) (NM_003024) Human Tagged ORF Clone Lentiviral Particle

SKU RC221701L3V

Lenti ORF particles, ITSN1 (Myc-DDK tagged) - Human intersectin 1 (SH3 domain protein) (ITSN1), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Intersectin 1
• Synonyms: ITSN; SH3D1A; SH3P17
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC221701).
• ACCN: NM_003024
• ORF Size: 5163 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_003024.2
• RefSeq Size: 6439 bp
• RefSeq ORF: 5166 bp
• Locus ID: 6453
• UniProt ID: Q15811
• Cytogenetics: 21q22.11
• Domains: C2, EFh, EH, PH, RhoGEF, SH3
• MW: 195.9 kDa
• Summary: The protein encoded by this gene is a cytoplasmic membrane-associated protein that indirectly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle recycling. This protein has been shown to interact with dynamin, CDC42, SNAP23, SNAP25, SPIN90, EPS15, EPN1, EPN2, and STN2. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been characterized so far. [provided by RefSeq, Jul 2008]