SPFH2 (ERLIN2) (NM_007175) Human Tagged ORF Clone Lentiviral Particle

SKU RC221700L4V

Lenti ORF particles, ERLIN2 (mGFP-tagged) - Human ER lipid raft associated 2 (ERLIN2), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: SPFH2
• Synonyms: C8orf2; Erlin-2; NET32; SPFH2; SPG18
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC221700).
• ACCN: NM_007175
• ORF Size: 1017 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_007175.5
• RefSeq Size: 4767 bp
• RefSeq ORF: 1020 bp
• Locus ID: 11160
• UniProt ID: O94905
• Cytogenetics: 8p11.23
• Domains: Band_7
• MW: 37.7 kDa
• Summary: This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]