PTF1A (NM_178161) Human Tagged ORF Clone Lentiviral Particle

SKU RC221496L4V

Lenti ORF particles, PTF1A (mGFP-tagged) - Human pancreas specific transcription factor, 1a (PTF1A), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: PTF1A
• Synonyms: bHLHa29; p48; PACA; PAGEN2; PTF1-p48
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC221496).
• ACCN: NM_178161
• ORF Size: 984 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_178161.1
• RefSeq Size: 987 bp
• RefSeq ORF: 987 bp
• Locus ID: 256297
• UniProt ID: Q7RTS3
• Cytogenetics: 10p12.2
• Protein Families: Embryonic stem cells, ES Cell Differentiation/IPS
• MW: 34.8 kDa
• Summary: This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. [provided by RefSeq, Jul 2008]