VMAT1 (SLC18A1) (NM_003053) Human Tagged ORF Clone Lentiviral Particle

SKU RC221148L4V

Lenti ORF particles, SLC18A1 (mGFP-tagged)-Human solute carrier family 18 (vesicular monoamine), member 1 (SLC18A1), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: VMAT1
• Synonyms: CGAT; VAT1; VMAT1
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC221148).
• ACCN: NM_003053
• ORF Size: 1575 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_003053.3
• RefSeq Size: 2770 bp
• RefSeq ORF: 1578 bp
• Locus ID: 6570
• UniProt ID: P54219
• Cytogenetics: 8p21.3
• Protein Families: Transmembrane
• Protein Pathways: Parkinson's disease
• MW: 56.3 kDa
• Summary: The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008]