VMAT1 (SLC18A1) Rabbit Polyclonal Antibody

SKU TA323893

Anti-SLC18A1 Rabbit Polyclonal Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 500-2000; WB positive control: A549 cells; IHC: 10-50; Positive control: Human brain; Predicted cell location: Cytoplasm
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 104-117 amino acids of human solute carrier family 18 (vesicular monoamine), member 1
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 56 kDa
• Gene Name: solute carrier family 18 member A1
• Database Link:
  NP_001135797
  P54219
• Background: The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles; using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs; including reserpine and tetrabenazine.
• Synonyms: CGAT; VAT1; VMAT1

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Parkinson's disease