EOMES (NM_005442) Human Tagged ORF Clone Lentiviral Particle

SKU RC221014L2V

Lenti ORF particles, EOMES (mGFP-tagged) - Human eomesodermin (EOMES), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: EOMES
• Synonyms: TBR2
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC221014).
• ACCN: NM_005442
• ORF Size: 2058 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_005442.2
• RefSeq Size: 2756 bp
• RefSeq ORF: 2061 bp
• Locus ID: 8320
• UniProt ID: O95936
• Cytogenetics: 3p24.1
• Domains: T-box
• Protein Families: Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors
• MW: 72.6 kDa
• Summary: This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]