TSH Receptor (TSHR) (NM_000369) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC220499L4V
- LentiORF®
Lenti ORF particles, TSHR (mGFP-tagged) - Human thyroid stimulating hormone receptor (TSHR), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP
Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | TSH Receptor |
Synonyms | CHNG1; hTSHR-I; LGR3 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_000369 |
ORF Size | 2292 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC220499).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000369.2 |
RefSeq Size | 4410 bp |
RefSeq ORF | 2295 bp |
Locus ID | 7253 |
UniProt ID | P16473 |
Cytogenetics | 14q31.1 |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | Autoimmune thyroid disease, Neuroactive ligand-receptor interaction |
MW | 86.83 kDa |
Gene Summary | The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] |
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