C12orf48 (PARPBP) (NM_017915) Human Tagged ORF Clone Lentiviral Particle

SKU RC220356L4V

Lenti ORF particles, PARPBP (mGFP-tagged) - Human chromosome 12 open reading frame 48 (C12orf48), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: C12orf48
• Synonyms: AROM; C12orf48; PARI
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC220356).
• ACCN: NM_017915
• ORF Size: 1737 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_017915.1
• RefSeq Size: 2175 bp
• RefSeq ORF: 1740 bp
• Locus ID: 55010
• UniProt ID: Q9NWS1
• Cytogenetics: 12q23.2
• Protein Families: Druggable Genome
• MW: 65.05 kDa
• Summary: Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. Antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. Binds single-strand DNA and poly(A) homopolymers. Positively regulate the poly(ADP-ribosyl)ation activity of PARP1; however such function may be indirect.[UniProtKB/Swiss-Prot Function]