IL16 (NM_004513) Human Tagged ORF Clone Lentiviral Particle

SKU RC220031L4V

Lenti ORF particles, IL16 (mGFP-tagged) - Human interleukin 16 (lymphocyte chemoattractant factor) (IL16), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: IL16
• Synonyms: LCF; NIL16; prIL-16; PRIL16
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC220031).
• ACCN: NM_004513
• ORF Size: 1893 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_004513.3
• RefSeq Size: 6193 bp
• RefSeq ORF: 1896 bp
• Locus ID: 3603
• UniProt ID: Q14005
• Cytogenetics: 15q25.1
• Domains: PDZ
• Protein Families: Druggable Genome, Secreted Protein
• MW: 66.5 kDa
• Summary: The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]