LASP1 (NM_006148) Human Tagged ORF Clone Lentiviral Particle

SKU RC219975L2V

Lenti ORF particles, LASP1 (mGFP-tagged) - Human LIM and SH3 protein 1 (LASP1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: LASP1
• Synonyms: Lasp-1; MLN50
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC219975).
• ACCN: NM_006148
• ORF Size: 783 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_006148.1
• RefSeq Size: 3846 bp
• RefSeq ORF: 786 bp
• Locus ID: 3927
• UniProt ID: Q14847
• Cytogenetics: 17q12
• Domains: LIM, NEBU, SH3
• Protein Families: Druggable Genome
• MW: 29.5 kDa
• Summary: This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012]