NIRF (UHRF2) (NM_152896) Human Tagged ORF Clone Lentiviral Particle

SKU RC219579L4V

Lenti ORF particles, UHRF2 (mGFP-tagged) - Human ubiquitin-like with PHD and ring finger domains 2 (UHRF2), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: NIRF
• Synonyms: NIRF; RNF107; TDRD23; URF2
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC219579).
• ACCN: NM_152896
• ORF Size: 2406 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_152896.1
• RefSeq Size: 3621 bp
• RefSeq ORF: 2409 bp
• Locus ID: 115426
• UniProt ID: Q96PU4
• Cytogenetics: 9p24.1
• Protein Families: Druggable Genome, Transcription Factors
• MW: 89.8 kDa
• Summary: This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012]