TDRD9 (NM_153046) Human Tagged ORF Clone Lentiviral Particle

SKU RC219472L4V

Lenti ORF particles, TDRD9 (mGFP-tagged)-Human tudor domain containing 9 (TDRD9), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: TDRD9
• Synonyms: C14orf75; HIG-1; HLS; NET54; SPGF30; SPNE
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC219472).
• ACCN: NM_153046
• ORF Size: 4146 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_153046.2, NP_694591.2
• RefSeq Size: 4782 bp
• RefSeq ORF: 4149 bp
• Locus ID: 122402
• UniProt ID: Q8NDG6
• Cytogenetics: 14q32.33
• MW: 155.5 kDa
• Summary: ATP-binding RNA helicase required during spermatogenesis (PubMed:28536242). Required to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Acts downstream of piRNA biogenesis: exclusively required for transposon silencing in the nucleus, suggesting that it acts as a nuclear effector in the nucleus together with PIWIL4.[UniProtKB/Swiss-Prot Function]