TAZ (NM_000116) Human Tagged ORF Clone Lentiviral Particle
SKU
RC218841L3V
Lenti ORF particles, TAZ (Myc-DDK tagged) - Human tafazzin (TAZ), nuclear gene encoding mitochondrial protein, transcript variant 1, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | TAZ |
Synonyms | BTHS; CMD3A; EFE; EFE2; G4.5; LVNCX; TAZ; Taz1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC218841).
|
ACCN | NM_000116 |
ORF Size | 876 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_000116.2 |
RefSeq Size | 1904 bp |
RefSeq ORF | 879 bp |
Locus ID | 6901 |
UniProt ID | Q16635 |
Cytogenetics | Xq28 |
Domains | Acyltransferase |
Protein Families | ES Cell Differentiation/IPS, Transmembrane |
MW | 33.3 kDa |
Summary | This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known. [provided by RefSeq, Jul 2008] |
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