RAPGEF5 (NM_012294) Human Tagged ORF Clone Lentiviral Particle

SKU RC218010L3V

Lenti ORF particles, RAPGEF5 (Myc-DDK tagged) - Human Rap guanine nucleotide exchange factor (GEF) 5 (RAPGEF5), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: RAPGEF5
• Synonyms: GFR; MR-GEF; REPAC
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218010).
• ACCN: NM_012294
• ORF Size: 2190 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_012294.3, NP_036426.3
• RefSeq Size: 6629 bp
• RefSeq ORF: 2652 bp
• Locus ID: 9771
• UniProt ID: Q92565
• Cytogenetics: 7p15.3
• MW: 84.5 kDa
• Summary: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]