PMS1 (NM_000534) Human Tagged ORF Clone Lentiviral Particle

SKU RC217412L2V

Lenti ORF particles, PMS1 (mGFP-tagged) - Human PMS1 postmeiotic segregation increased 1 (S. cerevisiae) (PMS1), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: PMS1
• Synonyms: HNPCC3; hPMS1; MLH2; PMSL1
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217412).
• ACCN: NM_000534
• ORF Size: 2796 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000534.3
• RefSeq Size: 3239 bp
• RefSeq ORF: 2799 bp
• Locus ID: 5378
• UniProt ID: P54277
• Cytogenetics: 2q32.2
• Domains: DNA_mis_repair, HATPase_c, HMG
• Protein Families: Druggable Genome, Transcription Factors
• MW: 105.7 kDa
• Summary: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]