KCNT2 (NM_198503) Human Tagged ORF Clone Lentiviral Particle

SKU RC216225L3V

Lenti ORF particles, KCNT2 (Myc-DDK tagged) - Human potassium channel, subfamily T, member 2 (KCNT2), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: KCNT2
• Synonyms: EIEE57; KCa4.2; SLICK; SLO2.1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC216225).
• ACCN: NM_198503
• ORF Size: 3405 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_198503.2, NP_940905.2
• RefSeq Size: 5909 bp
• RefSeq ORF: 3408 bp
• Locus ID: 343450
• UniProt ID: Q6UVM3
• Cytogenetics: 1q31.3
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane
• MW: 130.3 kDa
• Summary: Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels (PubMed:14684870, PubMed:16687497, PubMed:29069600). Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (PubMed:16687497) (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRM1 (PubMed:16687497).[UniProtKB/Swiss-Prot Function]