Pregnancy zone protein (PZP) (NM_002864) Human Tagged ORF Clone Lentiviral Particle

SKU RC215526L3V

Lenti ORF particles, PZP (Myc-DDK tagged) - Human pregnancy-zone protein (PZP), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Pregnancy zone protein
• Synonyms: CPAMD6
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC215526).
• ACCN: NM_002864
• ORF Size: 4446 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_002864.1
• RefSeq Size: 4615 bp
• RefSeq ORF: 4449 bp
• Locus ID: 5858
• Cytogenetics: 12p13.31
• Domains: A2M, A2M_N
• Protein Families: Druggable Genome
• MW: 163.7 kDa
• Summary: The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimer's disease patients. [provided by RefSeq, Dec 2016]