Neurotrophin 3 (NTF3) (NM_002527) Human Tagged ORF Clone Lentiviral Particle
SKU
RC214226L3V
Lenti ORF particles, NTF3 (Myc-DDK tagged) - Human neurotrophin 3 (NTF3), transcript variant 2, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | Neurotrophin 3 |
Synonyms | HDNF; NGF-2; NGF2; NT-3; NT3 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC214226).
|
ACCN | NM_002527 |
ORF Size | 771 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_002527.3 |
RefSeq Size | 1182 bp |
RefSeq ORF | 774 bp |
Locus ID | 4908 |
UniProt ID | P20783 |
Cytogenetics | 12p13.31 |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | MAPK signaling pathway, Neurotrophin signaling pathway |
MW | 29.4 kDa |
Summary | The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008] |
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