USP7 (NM_003470) Human Tagged ORF Clone Lentiviral Particle
SKU
RC213986L3V
Lenti ORF particles, USP7 (Myc-DDK tagged) - Human ubiquitin specific peptidase 7 (herpes virus-associated) (USP7), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | USP7 |
Synonyms | HAFOUS; HAUSP; TEF1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC213986).
|
ACCN | NM_003470 |
ORF Size | 3306 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_003470.1 |
RefSeq Size | 4022 bp |
RefSeq ORF | 3309 bp |
Locus ID | 7874 |
UniProt ID | Q93009 |
Cytogenetics | 16p13.2 |
Domains | MATH, UCH |
Protein Families | Druggable Genome, Protease |
MW | 128.1 kDa |
Summary | The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016] |
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