Kir4.1 (KCNJ10) (NM_002241) Human Tagged ORF Clone Lentiviral Particle

SKU RC213543L4V

Lenti ORF particles, KCNJ10 (mGFP-tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 10 (KCNJ10), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Kir4.1
• Synonyms: BIRK-10; KCNJ13-PEN; KIR1.2; KIR4.1; SESAME
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC213543).
• ACCN: NM_002241
• ORF Size: 1137 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_002241.2
• RefSeq Size: 4515 bp
• RefSeq ORF: 1140 bp
• Locus ID: 3766
• UniProt ID: P78508
• Cytogenetics: 1q23.2
• Domains: IRK
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane
• MW: 42.3 kDa
• Summary: This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes. [provided by RefSeq, Jul 2008]