ALKBH3 (NM_139178) Human Tagged ORF Clone Lentiviral Particle

SKU RC212873L3V

Lenti ORF particles, ALKBH3 (Myc-DDK tagged) - Human alkB, alkylation repair homolog 3 (E. coli) (ALKBH3), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: ALKBH3
• Synonyms: ABH3; DEPC-1; DEPC1; hABH3; PCA1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC212873).
• ACCN: NM_139178
• ORF Size: 841 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_139178.1
• RefSeq Size: 1520 bp
• RefSeq ORF: 861 bp
• Locus ID: 221120
• UniProt ID: Q96Q83
• Cytogenetics: 11p11.2
• Domains: 2OG-FeII_Oxy
• Protein Families: Druggable Genome
• MW: 33.2 kDa
• Summary: The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008]