LGR5 (NM_003667) Human Tagged ORF Clone Lentiviral Particle

SKU RC212825L3V

Lenti ORF particles, LGR5 (Myc-DDK tagged) - Human leucine-rich repeat containing G protein-coupled receptor 5 (LGR5), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: LGR5
• Synonyms: FEX; GPR49; GPR67; GRP49; HG38
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC212825).
• ACCN: NM_003667
• ORF Size: 2721 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_003667.2
• RefSeq Size: 2880 bp
• RefSeq ORF: 2724 bp
• Locus ID: 8549
• UniProt ID: O75473
• Cytogenetics: 12q21.1
• Domains: 7tm_1, LRR, LRRNT, LRR_PS, LRR_TYP
• Protein Families: Druggable Genome, GPCR, Transmembrane
• MW: 99.8 kDa
• Summary: The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]