Chimaerin 2 (CHN2) (NM_004067) Human Tagged ORF Clone Lentiviral Particle

SKU RC211342L3V

Lenti ORF particles, CHN2 (Myc-DDK tagged) - Human chimerin (chimaerin) 2 (CHN2), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Chimaerin 2
• Synonyms: ARHGAP3; BCH; CHN2-3; RHOGAP3
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC211342).
• ACCN: NM_004067
• ORF Size: 1404 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_004067.1
• RefSeq Size: 3461 bp
• RefSeq ORF: 1407 bp
• Locus ID: 1124
• UniProt ID: P52757
• Cytogenetics: 7p14.3
• Domains: DAG_PE-bind, RhoGAP, SH2
• MW: 53.9 kDa
• Summary: This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that contains a phorbol-ester/diacylglycerol (DAG)-type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG). Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, May 2014]