SPTSSB (NM_001040100) Human Tagged ORF Clone Lentiviral Particle

SKU RC210453L4V

Lenti ORF particles, SPTSSB (mGFP-tagged) - Human chromosome 3 open reading frame 57 (C3orf57), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: SPTSSB
• Synonyms: ADMP; C3orf57; SSSPTB
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210453).
• ACCN: NM_001040100
• ORF Size: 228 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001040100.1, NP_001035189.1
• RefSeq Size: 2306 bp
• RefSeq ORF: 231 bp
• Locus ID: 165679
• UniProt ID: Q8NFR3
• Cytogenetics: 3q26.1
• Protein Families: Transmembrane
• MW: 9.2 kDa
• Summary: Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTB is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010]