TPK1 (NM_022445) Human Tagged ORF Clone Lentiviral Particle

SKU RC209721L3V

Lenti ORF particles, TPK1 (Myc-DDK tagged) - Human thiamin pyrophosphokinase 1 (TPK1), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: TPK1
• Synonyms: HTPK1; PP20; THMD5
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209721).
• ACCN: NM_022445
• ORF Size: 729 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_022445.3
• RefSeq Size: 2449 bp
• RefSeq ORF: 732 bp
• Locus ID: 27010
• UniProt ID: Q9H3S4
• Cytogenetics: 7q35
• Domains: TPK_B1_binding, TPK_catalytic
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Thiamine metabolism
• MW: 27.2 kDa
• Summary: The protein encoded by this gene functions as a homodimer and catalyzes the conversion of thiamine to thiamine pyrophosphate, a cofactor for some enzymes of the glycolytic and energy production pathways. Defects in this gene are a cause of thiamine metabolism dysfunction syndrome-5. [provided by RefSeq, Apr 2017]