ZNF281 (NM_012482) Human Tagged ORF Clone Lentiviral Particle

SKU RC209243L3V

Lenti ORF particles, ZNF281 (Myc-DDK tagged) - Human zinc finger protein 281 (ZNF281), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: ZNF281
• Synonyms: GZP1; ZBP-99; ZBP99; ZNP-99
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209243).
• ACCN: NM_012482
• ORF Size: 2685 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_012482.3, NP_036614.1
• RefSeq Size: 4904 bp
• RefSeq ORF: 2688 bp
• Locus ID: 23528
• UniProt ID: Q9Y2X9
• Cytogenetics: 1q32.1
• Domains: zf-C2H2
• Protein Families: ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transcription Factors
• MW: 96.9 kDa
• Summary: Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity). Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes.[UniProtKB/Swiss-Prot Function]