DPH4 (DNAJC24) (NM_181706) Human Tagged ORF Clone Lentiviral Particle

SKU RC209088L4V

Lenti ORF particles, DNAJC24 (mGFP-tagged) - Human DnaJ (Hsp40) homolog, subfamily C, member 24 (DNAJC24), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: DPH4
• Synonyms: DPH4; JJJ3; ZCSL3
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209088).
• ACCN: NM_181706
• ORF Size: 444 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_181706.4, NP_859057.3
• RefSeq Size: 3000 bp
• RefSeq ORF: 450 bp
• Locus ID: 120526
• UniProt ID: Q6P3W2
• Cytogenetics: 11p13
• MW: 17 kDa
• Summary: Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008]