SCYL2 (NM_017988) Human Tagged ORF Clone Lentiviral Particle

SKU RC209051L4V

Lenti ORF particles, SCYL2 (mGFP-tagged)-Human SCY1-like 2 (S. cerevisiae) (SCYL2), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: SCYL2
• Synonyms: AMC4; AMCNACC; CVAK104
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209051).
• ACCN: NM_017988
• ORF Size: 2787 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_017988.4
• RefSeq Size: 3818 bp
• RefSeq ORF: 2790 bp
• Locus ID: 55681
• UniProt ID: Q6P3W7
• Cytogenetics: 12q23.1
• Protein Families: Druggable Genome, Protein Kinase
• MW: 103.5 kDa
• Summary: The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015]