PTPLAD1 (HACD3) (NM_016395) Human Tagged ORF Clone Lentiviral Particle

SKU RC208931L4V

Lenti ORF particles, HACD3 (mGFP-tagged) - Human protein tyrosine phosphatase-like A domain containing 1 (PTPLAD1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: PTPLAD1
• Synonyms: B-IND1; BIND1; HSPC121; PTPLAD1
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC208931).
• ACCN: NM_016395
• ORF Size: 1086 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_016395.2
• RefSeq Size: 3213 bp
• RefSeq ORF: 1089 bp
• Locus ID: 51495
• UniProt ID: Q9P035
• Cytogenetics: 15q22.31
• Domains: PTPLA
• Protein Families: Transmembrane
• MW: 43 kDa
• Summary: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May be involved in Rac1-signaling pathways leading to the modulation of gene expression. Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization (PubMed:25687571).[UniProtKB/Swiss-Prot Function]