OLIG2 (NM_005806) Human Tagged ORF Clone Lentiviral Particle
SKU
RC208209L4V
Lenti ORF particles, OLIG2 (mGFP-tagged) - Human oligodendrocyte lineage transcription factor 2 (OLIG2), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | OLIG2 |
Synonyms | BHLHB1; bHLHe19; OLIGO2; PRKCBP2; RACK17 |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC208209).
|
ACCN | NM_005806 |
ORF Size | 969 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_005806.2, NP_005797.1 |
RefSeq Size | 2505 bp |
RefSeq ORF | 972 bp |
Locus ID | 10215 |
UniProt ID | Q13516 |
Cytogenetics | 21q22.11 |
Domains | HLH |
Protein Families | Druggable Genome, Transcription Factors |
MW | 32.4 kDa |
Summary | This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008] |
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