DCUN1D3 (NM_173475) Human Tagged ORF Clone Lentiviral Particle
SKU
RC208082L2V
Lenti ORF particles, DCUN1D3 (mGFP-tagged) - Human DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae) (DCUN1D3), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | DCUN1D3 |
Synonyms | 44M2.4; SCCRO3 |
Vector | pLenti-C-mGFP |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC208082).
|
ACCN | NM_173475 |
ORF Size | 912 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_173475.1, NP_775746.1 |
RefSeq Size | 2886 bp |
RefSeq ORF | 915 bp |
Locus ID | 123879 |
UniProt ID | Q8IWE4 |
Cytogenetics | 16p12.3 |
MW | 34.3 kDa |
Summary | Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane (PubMed:25349211). When overexpressed in transformed cells, may promote mesenchymal to epithelial-like changes and inhibit colony formation in soft agar (PubMed:25349211).[UniProtKB/Swiss-Prot Function] |
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