PRKAR1B (NM_002735) Human Tagged ORF Clone Lentiviral Particle

SKU RC207809L4V

Lenti ORF particles, PRKAR1B (mGFP-tagged) - Human protein kinase, cAMP-dependent, regulatory, type I, beta (PRKAR1B), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: PRKAR1B
• Synonyms: PRKAR1
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC207809).
• ACCN: NM_002735
• ORF Size: 1143 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_002735.1
• RefSeq Size: 2512 bp
• RefSeq ORF: 1146 bp
• Locus ID: 5575
• UniProt ID: P31321
• Cytogenetics: 7p22.3
• Protein Families: Druggable Genome
• Protein Pathways: Apoptosis, Insulin signaling pathway
• MW: 43.1 kDa
• Summary: The protein encoded by this gene is a regulatory subunit of cyclic AMP-dependent protein kinase A (PKA), which is involved in the signaling pathway of the second messenger cAMP. Two regulatory and two catalytic subunits form the PKA holoenzyme, disbands after cAMP binding. The holoenzyme is involved in many cellular events, including ion transport, metabolism, and transcription. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2015]