PHF17 (JADE1) (NM_024900) Human Tagged ORF Clone Lentiviral Particle

SKU RC207135L2V

Lenti ORF particles, JADE1 (mGFP-tagged) - Human PHD finger protein 17 (PHF17), transcript variant S, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: PHF17
• Synonyms: PHF17
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC207135).
• ACCN: NM_024900
• ORF Size: 1527 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_024900.3
• RefSeq Size: 4204 bp
• RefSeq ORF: 1530 bp
• Locus ID: 79960
• UniProt ID: Q6IE81
• Cytogenetics: 4q28.2
• Domains: PHD
• Protein Families: Druggable Genome, Transcription Factors
• MW: 58.4 kDa
• Summary: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function.[UniProtKB/Swiss-Prot Function]