Centaurin gamma 1 (AGAP2) (NM_014770) Human Tagged ORF Clone Lentiviral Particle

SKU RC206993L3V

Lenti ORF particles, AGAP2 (Myc-DDK tagged) - Human ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (AGAP2), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Centaurin gamma 1
• Synonyms: CENTG1; GGAP2; PIKE
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206993).
• ACCN: NM_014770
• ORF Size: 2508 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_014770.2
• RefSeq Size: 4860 bp
• RefSeq ORF: 2511 bp
• Locus ID: 116986
• UniProt ID: Q99490
• Cytogenetics: 12q14.1
• Domains: ANK, ArfGap, PH, RAB, RAS
• Protein Pathways: Endocytosis
• MW: 90.5 kDa
• Summary: The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]