ALS (IGFALS) (NM_004970) Human Tagged ORF Clone Lentiviral Particle
SKU
RC206542L4V
Lenti ORF particles, IGFALS (mGFP-tagged) - Human insulin-like growth factor binding protein, acid labile subunit (IGFALS), transcript variant 2, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | ALS |
Synonyms | ACLSD; ALS |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC206542).
|
ACCN | NM_004970 |
ORF Size | 1815 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_004970.1 |
RefSeq Size | 2168 bp |
RefSeq ORF | 1818 bp |
Locus ID | 3483 |
UniProt ID | P35858 |
Cytogenetics | 16p13.3 |
Protein Families | Druggable Genome, Secreted Protein |
MW | 66.1 kDa |
Summary | The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
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