Fibromodulin (FMOD) (NM_002023) Human Tagged ORF Clone Lentiviral Particle

SKU RC206534L3V

Lenti ORF particles, FMOD (Myc-DDK tagged) - Human fibromodulin (FMOD), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Fibromodulin
• Synonyms: FM; SLRR2E
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206534).
• ACCN: NM_002023
• ORF Size: 1128 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_002023.3
• RefSeq Size: 3271 bp
• RefSeq ORF: 1131 bp
• Locus ID: 2331
• UniProt ID: Q06828
• Cytogenetics: 1q32.1
• Domains: LRR, LRRNT, LRR_BAC, LRR_PS, LRR_TYP
• Protein Families: Druggable Genome, Secreted Protein
• MW: 43.2 kDa
• Summary: Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]