KDELC2 (POGLUT3) (NM_153705) Human Tagged ORF Clone Lentiviral Particle
SKU
RC206171L3V
Lenti ORF particles, KDELC2 (Myc-DDK tagged) - Human KDEL (Lys-Asp-Glu-Leu) containing 2 (KDELC2), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | POGLUT3 |
Synonyms | KDELC2 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC206171).
|
ACCN | NM_153705 |
ORF Size | 1521 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_153705.2 |
RefSeq Size | 4311 bp |
RefSeq ORF | 1524 bp |
Locus ID | 143888 |
UniProt ID | Q7Z4H8 |
Cytogenetics | 11q22.3 |
Domains | CAP10 |
MW | 58.5 kDa |
Summary | Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C (PubMed:30127001). Can also catalyze the transfer of xylose from UDP-xylose but less efficiently (PubMed:30127001). Specifically targets extracellular EGF repeats of proteins such as NOTCH1 and NOTCH3 (PubMed:30127001). May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway (PubMed:30127001).[UniProtKB/Swiss-Prot Function] |
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