NUAK2 (NM_030952) Human Tagged ORF Clone Lentiviral Particle

SKU RC205740L4V

Lenti ORF particles, NUAK2 (mGFP-tagged) - Human NUAK family, SNF1-like kinase, 2 (NUAK2), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: NUAK2
• Synonyms: SNARK
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205740).
• ACCN: NM_030952
• ORF Size: 1884 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_030952.1, NP_112214.1
• RefSeq Size: 3443 bp
• RefSeq ORF: 1887 bp
• Locus ID: 81788
• UniProt ID: Q9H093
• Cytogenetics: 1q32.1
• Protein Families: Druggable Genome, Protein Kinase
• MW: 69.6 kDa
• Summary: Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.[UniProtKB/Swiss-Prot Function]