DNase gamma (DNASE1L3) (NM_004944) Human Tagged ORF Clone Lentiviral Particle

SKU RC205611L3V

Lenti ORF particles, DNASE1L3 (Myc-DDK tagged) - Human deoxyribonuclease I-like 3 (DNASE1L3), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: DNase gamma
• Synonyms: DHP2; DNAS1L3; LSD; SLEB16
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205611).
• ACCN: NM_004944
• ORF Size: 915 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_004944.2
• RefSeq Size: 1076 bp
• RefSeq ORF: 918 bp
• Locus ID: 1776
• UniProt ID: Q13609
• Cytogenetics: 3p14.3
• Domains: DNaseIc, Exo_endo_phos
• Protein Families: Druggable Genome
• MW: 35.5 kDa
• Summary: This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]