MANBA (NM_005908) Human Tagged ORF Clone Lentiviral Particle

SKU RC204862L3V

Lenti ORF particles, MANBA (Myc-DDK tagged) - Human mannosidase, beta A, lysosomal (MANBA), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: MANBA
• Synonyms: MANB1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204862).
• ACCN: NM_005908
• ORF Size: 2637 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_005908.3
• RefSeq Size: 3311 bp
• RefSeq ORF: 2640 bp
• Locus ID: 4126
• UniProt ID: O00462
• Cytogenetics: 4q24
• Domains: Glyco_hydro_2_C
• Protein Pathways: Lysosome, Other glycan degradation
• MW: 100.9 kDa
• Summary: This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement. [provided by RefSeq, Jul 2008]