beta Sarcoglycan (SGCB) (NM_000232) Human Tagged ORF Clone Lentiviral Particle

SKU RC204699L4V

Lenti ORF particles, SGCB (mGFP-tagged) - Human sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (SGCB), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: beta Sarcoglycan
• Synonyms: A3b; LGMD2E; LGMDR4; SGC
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204699).
• ACCN: NM_000232
• ORF Size: 954 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000232.3
• RefSeq Size: 4295 bp
• RefSeq ORF: 957 bp
• Locus ID: 6443
• UniProt ID: Q16585
• Cytogenetics: 4q12
• Domains: sarcoglycan
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Viral myocarditis
• MW: 34.8 kDa
• Summary: This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.[provided by RefSeq, Oct 2008]